Imaging
Equipment
Confocal Laser Scanning Microscope
(Zeiss LSM 980)
Multi-view Light-sheet Microscope
(Leica Viventis Deep)
Widefield Microscope
(Leica DMi8)
(Zeiss LSM 980)
Multi-view Light-sheet Microscope
(Leica Viventis Deep)
Widefield Microscope
(Leica DMi8)
Methods & Services (only in cooperation)
Project support
Advice in sample preparation and assay development
Imaging of complex tissues
Data management and analysis
Advice in sample preparation and assay development
Imaging of complex tissues
Data management and analysis
Responsible Person
Andreas Hocke
Valentin Dunsing-Eichenauer
Valentin Dunsing-Eichenauer
Booking
upon request
Team
Clade 2.3.4.4b H5N1 influenza A virus exhibits high infectivity in human respiratory tract models
Anna Löwa, Matthias Budt, Anita Balázs, Victor Sikora, Mark Melzer, Tihomir Rubil, Annika E Pfeiffer, Mara Fischer, Maren Mieth, Katharina Hellwig, Emanuel Wyler, Diego G Diel, Mario Tönnies, Torsten T Bauer, Mareike Graff, Jens Neudecker, Jens-C Rückert, Marcus A Mall, Achim D Gruber, Markus Landthaler, Lisa Buchauer, Stefan Hippenstiel, Thorsten Wolff, Andreas C Hocke
Journal of Infection
12.03.2026
Spatial patterning of contractility by a self-organized mechanogen activity gradient underlies Drosophila gastrulation
Gayatri Mundhe, Valentin Dunsing-Eichenauer, Jean-Marc Philippe, Élise Da Silva, Claudio Collinet & Thomas Lecuit
Nature Communications
23.01.2026
Lung tumouroids as a testing platform for precision CAR T cell therapy
Lukas Ehlen, Martí Farrera-Sal, Martin Szyska, Janine Arndt, Simon Schallenberg, Cedric Scholz, Mingxing Yang, Claudia Vollbrecht, Anna Löwa, Rebecca Friedrich, Marco Mai, Lena Peter, Samira Picht, Sarah Schulenberg, Daniel Geray, Gabriela Korus, Anke Sommerfeld, Denise Treue, Julia Strauchmann, Aron Elsner, Jonas Kath, Valeria Fernandez Vallone, Maria Joosten, Franka Klatte-Schulz, Ansgar Petersen, Harald Stachelscheid, Dimitrios L. Wagner, Claudia Spies, Jens-Carsten Rückert, Andreas C. Hocke, Julia K. Polansky, Regina Stark, Oliver Klein & Michael Schmueck-Henneresse
Nature Biomedical Engineering
21.01.2026
A quantitative pipeline for whole-mount deep imaging and analysis of multi-layered organoids across scales
Alice Gros, Jules Vanaret, Valentin Dunsing-Eichenauer, Agathe Rostan, Philippe Roudot, Pierre-François Lenne, Léo Guignard, Sham Tlili
eLife
13.01.2026
Ex vivo infection model for Francisella using human lung tissue
Kristin Köppen, Diana Fatykhova , Gudrun Holland, Jessica Rauch, Dennis Tappe, Mareike Graff, Kerstin Rydzewski, Andreas C Hocke, Stefan Hippenstiel, Klaus Heuner
Frontiers in Cellular and Infection Microbiology
10.07.2023
The unremarkable alveolar epithelial glycocalyx: a thorium dioxide-based electron microscopic comparison after heparinase or pneumolysin treatment
Sara Timm, Marie Lettau, Jan Hegermann, Maria Linda Rocha, Sarah Weidenfeld, Diana Fatykhova, Birgitt Gutbier, Geraldine Nouailles, Elena Lopez-Rodriguez, Andreas Hocke, Stefan Hippenstiel, Martin Witzenrath, Wolfgang M Kuebler, Matthias Ochs
Histochemistry and Cell Biology
29.06.2023
State-of-the-art analytical methods of viral infections in human lung organoids
Morris Baumgardt, Maren Hülsemann, Anna Löwa, Diana Fatykhova, Karen Hoffmann, Mirjana Kessler, Maren Mieth, Katharina Hellwig, Doris Frey, Alina Langenhagen, Anne Voss, Benedikt Obermayer, Emanuel Wyler, Simon Dökel, Achim D Gruber, Ulf Tölch, Stefan Hippenstiel, Andreas C Hocke, Katja Hönzke
PLoS One
20.12.2022
Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection ans vaccination
Lucie Loyal, Julian Braun, Larissa Henze, Beate Kruse, Manuela Dingeldey, Ulf Reimer, Florian Kern, Tatjana Schwarz, Maike Mangold, Clara Unger, Friederike Dörfler, Shirin Kadler, Jennifer Rosowski, Kübrah Gürcan, Zehra Uyar-Aydin, Marco Frentsch, Florian Kurth, Karsten Schnatbaum, Maren Eckey, Stefan Hippenstiel, Andreas Hocke, Marcel A Müller, Birgit Sawitzki, Stefan Miltenyi, Friedemann Paul, Marcus A Mall, Holger Wenschuh, Sebastian Voigt, Christian Drosten, Roland Lauster, Nils Lachman, Leif-Erik Sander, Victor M Corman, Jobst Röhmel, Lil Meyer-Arndt, Andreas Thiel, Claudia Giesecke-Thiel
Science
08.10.2021
Bioprinted Multi-Cell Type Lung Model for the Study of Viral Inhibitors
Johanna Berg, Zia Weber, Mona Fechler-Bitteti, Andreas C Hocke, Stefan Hippenstiel, Laura Elomaa, Marie Weinhart, Jens Kurreck
Viruses
11.08.2021
SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19
Julian Braun, Lucie Loyal, Marco Frentsch, Daniel Wendisch, Philipp Georg, Florian Kurth, Stefan Hippenstiel, Manuela Dingeldey, Beate Kruse, Florent Fauchere, Emre Baysal, Maike Mangold, Larissa Henze, Roland Lauster, Marcus A Mall, Kirsten Beyer, Jobst Röhmel, Sebastian Voigt, Jürgen Schmitz, Stefan Miltenyi, Ilja Demuth, Marcel A Müller, Andreas Hocke, Martin Witzenrath, Norbert Suttorp, Florian Kern, Ulf Reimer, Holger Wenschuh, Christian Drosten, Victor M Corman, Claudia Giesecke-Thiel, Leif-Erik Sander, Andreas Thiel
Nature
29.07.2020