TissUse GmbH

Organs-on-a-Chip & Organoids

Equipment
• Multi-Organ-Chip control units (TissUse)
• Chip production equipment
• Microinjection device
• Hypoxia incubator
Methods and Services (only in cooperation)
• Project support
• Advice on chip design and experimental planning
• Vascularization of microfluidic systems
• Microinjection of organoids with microbiota (infection models)
• Pathogen lab (culture of pathogens)
• CRISPR cloning
Responsible Persons
Sina Bartfeld
Mark Rosowski
Mar Reines
Booking
upon request

Team

Medical Biotechnology in cooperation with

Tissuse logo
Mark Rosowski
Facility Lead Organ-on-a-Chip, Si-M Council Member, Researcher

Contact

Mar Reines
Researcher

Contact

Sina Bartfeld
Co-Spokesperson, Researcher, Facility Lead Organoids

Lab Homepage

State-of-the-art analytical methods of viral infections in human lung organoids
Morris Baumgardt, Maren Hülsemann, Anna Löwa, Diana Fatykhova, Karen Hoffmann, Mirjana Kessler, Maren Mieth, Katharina Hellwig, Doris Frey, Alina Langenhagen, Anne Voss, Benedikt Obermayer, Emanuel Wyler, Simon Dökel, Achim D Gruber, Ulf Tölch, Stefan Hippenstiel, Andreas C Hocke, Katja Hönzke
PLoS One
20.12.2022
Helicobacter pylori shows tropism to gastric differentiated pit cells dependent on urea chemotaxis
Carmen Aguilar, Mindaugas Pauzuolis, Malvika Pompaiah, Ehsan Vafadarnejad, Panagiota Arampatzi, Mara Fischer, Dominik Narres, Mastura Neyazi, Özge Kayisoglu, Thomas Sell, Nils Blüthgen, Markus Morkel, Armin Wiegering, Christoph-Thomas Germer, Stefan Kircher, Andreas Rosenwald, Antoine-Emmanuel Saliba, Sina Bartfeld
Nature Communications
05.10.2022
Editorial: 3D tissue models in infection research
Vera Kozjak-Pavlovic, Wenxia Song, Sina Bartfeld, Marco Metzger
Frontiers in Cellular and Infection Microbiology
22.07.2022
An Individual Patient's "Body" on Chips-How Organismoid Theory Can Translate Into Your Personal Precision Therapy Approach
Uwe Marx, Enrico Accastelli, Rhiannon David, Hendrik Erfurth, Leopold Koenig, Roland Lauster, Anja Patricia Ramme, Petra Reinke, Hans-Dieter Volk, Annika Winter, Eva-Maria Dehne
Frontiers in Medicine
13.09.2021
Gastrointestinal epithelial innate immunity-regionalization and organoids as new model
Özge Kayisoglu, Nicolas Schlegel, Sina Bartfeld
Journal of Molecular Medicine
04.02.2021
Realizing the potential of organoids - an interview with Hans Clevers
Sina Bartfeld
Journal of Molecular Medicine
19.01.2021