Single-Cell Unit
Equipment
BD Rhapsody HT Xpress System (Scanner+HT Xpress)
Chromium X
Xenium Analyzer
PhenoCycler
MiSeq
Implen Nanophotometer
Chromium X
Xenium Analyzer
PhenoCycler
MiSeq
Implen Nanophotometer
Methods & Services (only in cooperation)
Project support
(Single-cell) library preparation
Support in data management and analysis
(Single-cell) library preparation
Support in data management and analysis
Responsible Person
Birgit Sawitzki
Access
upon request
Team
The AICL-KLRF1 axis supports CD4-CD8 T cellcommunication and cytokine competence inpre-exhausted CD8+ T cells
Matthias Barone, Stefan Peidli, Anika Neuschulz, Karla Riesterer, Christina Iwert, Laia Junquera, Somesh Sai, Olufemi Bolaji, Diana Bakoueva, Christine Appelt, Benedikt Obermayer, Bertram Klinger, Alexandra Trinks, Anja Sieber, Nils Blüthgen & Birgit Sawitzki
EMBO reports
18.03.2026
Rewired type I IFN signaling is linked to age-dependent differences in COVID-19
Petrov L, Brumhard S, Wisniewski S, Georg P, Hillus D, Hiller A, Astaburuaga-García R, Blüthgen N, Wyler E, Vogt K, Dey HP, von Stillfried S, Iwert C, Bülow RD, Märkl B, Maas L, Langner C, Meyer T, Loske J, Eils R, Lehmann I, Ondruschka B, Ralser M, Trimpert J, Boor P, Bedoui S, Meisel C, Mall MA, Corman VM, Sander LE, Röhmel J, Sawitzki B
Cell Reports. Medicine
19.08.2025
Aging and Viral Evolution Impair Immunity Against Dominant Pan-Coronavirus-Reactive T Cell Epitope
Loyal L, Jürchott K, Reimer U, Meyer-Arndt L, Henze L, Mages N, Kostrzanowski J, Reus B, Mangold M, Kruse B, Dingeldey M, Sawitzki B, Michel J, Grossegesse M, Schnatbaum K, Wenschuh H, Nitsche A, Lachmann N, Timmermann B, Giesecke-Thiel C, Braun J, Kern F, Thiel A
European Journal of Immunology
28.07.2025
The cellular and molecular cardiac tissue responses in human inflammatory cardiomyopathies after SARS-CoV-2 infection and COVID-19 vaccination
Maatz H, Lindberg EL, Adami E, López-Anguita N, Perdomo-Sabogal A, Cocera Ortega L, Patone G, Reichart D, Myronova A, Schmidt S, Elsanhoury A, Klein O, Kühl U, Wyler E, Landthaler M, Yousefian S, Haas S, Kurth F, Teichmann SA, Oudit GY, Milting H, Noseda M, Seidman JG, Seidman CE, Heidecker B, Sander LE, Sawitzki B, Klingel K, Doeblin P, Kelle S, Van Linthout S, Hubner N, Tschöpe C
Nature Cardiovascular Research
24.02.2025
Haunting innate immune memories of COVID-19
Birgit Sawitzki
Cell
31.08.2023
SARS-CoV-2 mRNA vaccinations fail to elicit humoral and cellular immune responses in patients with multiple sclerosis receiving fingolimod
Lil Meyer-Arndt, Julian Braun, Florent Fauchere Kanika Vanshylla , Lucie Loyal, Larissa Henze, Beate Kruse, Manuela Dingeldey, Karsten Jürchott, Maike Mangold, Ardit Maraj, Andre Braginets, Chotima Böttcher , Andreas Nitsche, Kathrin de la Rosa, Christoph Ratswohl, Birgit Sawitzki, Pavlo Holenya, Ulf Reimer, Leif E Sander, Florian Klein, Friedemann Paul, Judith Bellmann-Strobl, Andreas Thiel, Claudia Giesecke-Thiel
BMJ nerology, Neurosurgery & Psychiatry
14.07.2023
RECAST: Study protocol for an observational study for the understanding of the increased REsilience of Children compared to Adults in SARS-CoV-2 infecTion
Sebastian Stricker, Niklas Ziegahn, Martin Karsten, Thomas Boeckel, Heike Stich-Boeckel, Jakob Maske, Evelyn Rugo, Anita Balazs, Pamela Millar Büchner, Chantip Dang-Heine, Valentin Schriever, Roland Eils, Irina Lehmann, Leif E Sander, Markus Ralser, Victor M Corman, Marcus A Mall, Birgit Sawitzki, Jobst Roehmel
BMJ Open
17.04.2023
Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection ans vaccination
Lucie Loyal, Julian Braun, Larissa Henze, Beate Kruse, Manuela Dingeldey, Ulf Reimer, Florian Kern, Tatjana Schwarz, Maike Mangold, Clara Unger, Friederike Dörfler, Shirin Kadler, Jennifer Rosowski, Kübrah Gürcan, Zehra Uyar-Aydin, Marco Frentsch, Florian Kurth, Karsten Schnatbaum, Maren Eckey, Stefan Hippenstiel, Andreas Hocke, Marcel A Müller, Birgit Sawitzki, Stefan Miltenyi, Friedemann Paul, Marcus A Mall, Holger Wenschuh, Sebastian Voigt, Christian Drosten, Roland Lauster, Nils Lachman, Leif-Erik Sander, Victor M Corman, Jobst Röhmel, Lil Meyer-Arndt, Andreas Thiel, Claudia Giesecke-Thiel
Science
08.10.2021